Posterior probability of linkage analysis of autism dataset identifies linkage to chromosome 16
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چکیده
منابع مشابه
Linkage of Parkinson’s disease in two very early onset siblings to a locus on chromosome 1
Parkinson’s disease (PD) is a prevalent neurodegenerative disease that usually affects individuals over 50 years of age. Age at onset in a small subset of PD cases is considerably lower, and these are considered early-onset PD (EOPD) patients. Most PD cases appear sporadic, but approximately 15% are familial, and some of the familial cases exhibit Mendelian inheritance. Genetic analysis of fami...
متن کاملLinkage analysis of chromosome 2q in osteoarthritis.
BACKGROUND In independent linkage studies chromosome 2q11-q24 and chromosome 2q23-35 have previously been implicated as regions potentially harbouring susceptibility loci for osteoarthritis (OA). OBJECTIVE To test chromosome 2q for linkage to idiopathic osteoarthritis. METHODS Using a cohort of 481 OA families that each contained at least one affected sibling pair with severe end-stage dise...
متن کاملanalysis of ruin probability for insurance companies using markov chain
در این پایان نامه نشان داده ایم که چگونه می توان مدل ریسک بیمه ای اسپیرر اندرسون را به کمک زنجیره های مارکوف تعریف کرد. سپس به کمک روش های آنالیز ماتریسی احتمال برشکستگی ، میزان مازاد در هنگام برشکستگی و میزان کسری بودجه در زمان وقوع برشکستگی را محاسبه کرده ایم. هدف ما در این پایان نامه بسیار محاسباتی و کاربردی تر از روش های است که در گذشته برای محاسبه این احتمال ارائه شده است. در ابتدا ما نشا...
15 صفحه اولLinkage of essential hypertension to chromosome 18q.
We performed a genomewide scan with 904 microsatellite markers using 120 extended Icelandic families with 490 hypertensive patients. The families were identified by cross-matching a list of hypertensive patients from the Hypertension Clinic of the University Hospital (Landspitalinn) in Iceland with a genealogy database of the entire Icelandic nation. After adding 5 markers, we found linkage to ...
متن کاملCombined Linkage and Association Analysis of the NARAC Dataset
In this report, we present the results of two novel statistical approaches for the detection of disease susceptibility loci when applied to a dataset on Rheumatoid Arthritis (RA), ascertained by the North American Rheumatoid Arthritis Consortium (NARAC) and provided as part of the GAW15 datasets. The two methods are complementary; the first method tests for linkage, while the second one for ass...
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ژورنال
عنوان ژورنال: Psychiatric Genetics
سال: 2008
ISSN: 0955-8829
DOI: 10.1097/ypg.0b013e3282f9b48e